Education

2009.10-2013.10，University of Cambridge, Chemistry, PhD

2005.07-2009.07, Sun Yat-sen University, Polymer Materials and Engineering, BEng

Professional Experience

2020.08-now, Tsinghua University, Shenzhen International Graduate School, Associate Professor

2017.09-2020.08, Tsinghua-Berkeley Shenzhen Institute, Assistant Professor

2013.11-2017.08, University of Oxford, Postdoctoral Researcher

Current Courses

Precision Diagnosis Platform Design and Therapeutics Application，SIGS

Introduction to Mechanobiology, SIGS

Advances in Regenerative Medicine, SIGS

Medical Science Research, SIGS

Research Interests

Synthetic organoid technology for drug discovery, development and regenerative medicine,

Biomanufacturing technology and equipment R&D

Computational Biology

Selected Publications

[1] Ma, Shaohua*; Wang, Wanlong; Zhou, Jiaqi; Liao, Shangfeng; Hai, Cheng; Hou, Yibo; Zhou, Zhichun; Wang, Zitian; Su, Yingshi; Zhu, Yu; Dai, Xiaoyong; Zhao, Yuan; Liao, Sha; Cai, Yongde*; Xu, Xun*; Lamination-based Organoid Spatially Resolved Transcriptomics (LOSRT) Technique for Primary Lung and Liver Organoid Characterization, Proc. Natl. Acad. Sci., 2024, 121, e2408939121.

[2] Yang, Haowei; Li, Jiawei; Zheng, Yichao; Cao, Yuanxiong; Zhu, Yu; Sang, Gan; Galan, Edgar A; Ruan, Chuqian; Ma, Wilson M.J.; Dai, Xiaoyong; Cai, Yongde*; Ma, Shaohua*; Ultra-small tissue compatible organoid printer for rapid and controllable modeling of respiratory organoids, Device (Cell Press), 2024, 2: 100420.

[3] Zheng, Yichao; Han, Fei; Wu, Zhengyu; Wang, Bingjie; Chen, Xingchi; Boulouis, Caroline; Jiang, Yuebin; Ho, Amanda; He, Dan; Sia, Wan Rong; Mak, Jeffrey Y.W.; Fairlie, David P.; Wang, Lin-Fa; Sandberg, Johan K.; Lobie, Peter E.; Ma, Shaohua*; Leeansyah, Edwin*; MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis, Science Advances, 2024, 10: eadn6331.

[4] Zheng, Yichao; Tian, Qinyong; Yang, Haowei; Cai, Yongde; Zhang, Jiaxin; Wu, Yifen; Zhu, Shuo; Qiu, Zuocheng; Lin, Yimin; Hong, Jiangquan; Zhang, Yi; Dockrell, David; Ma, Shaohua*; Identification of nicotinic acetylcholine receptor for N-acetylcysteine to rescue nicotine induced injury using beating cilia in primary tissue derived airway organoids, Advanced Science, 2024, 2407054.

[5] Zhou, Jiaqi; Huang, Yi-chun; Wang, Wanlong; Li, Jiawei; Hou, Yibo; Yi, Ziqi; Yang, Haowei; Hu, Keer; Zhu, Yu; Wang, Zitian; Ma, Shaohua*; Chronotoxici-plate containing droplet engineered rhythmic liver organoids for drug toxicity evaluation, Advanced Science, 2024, 11: 2305925.

[6] Feng, Yilin; Fan, Jiaqi; Cheng, Yifan; Dai, Qionghai; Ma, Shaohua*; Stress regulates Alzheimer's disease progression via selective enrichment of CD8+ T cells, Cell Reports, 2023, 42(10): 113313.

[7] Tang, Xiaowei; Wang, Zitian; Khutsishvili, David; Cheng, Yifan; Wang, Jiaqi; Tang, Jiyuan; Ma, Shaohua*; Volumetric compression by heterogeneous scaffold embedding promotes cerebral organoid maturation and does not impede growth, Cell Systems, 2023, 14(10): 872-882.e3.

[8] Cao, Yuanxiong; Tan, Jiayi; Zhao, Haoran; Deng, Ting; Hu, Yunxia; Zeng, Junhong; Li, Jiawei; Cheng, Yifan; Tang, Jiyuan; Hu, Zhiwei; Hu, Keer; Xu, Bing; Wang, Zitian; Wu, Yaojiong; Lobie, Peter E; Ma, Shaohua*; Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration, Nature Communications, 2022, 13: 7463.

[9] Fan, Jiaqi; Feng, Yilin; Cheng, Yifan; Wang, Zitian; Zhao, Haoran; Galan, Edgar A.; Liao, Quanxing; Cui, Shuzhong; Zhang, Weijie; Ma, Shaohua*; Multiplex gene quantification as digital markers for extremely rapid evaluation of chemo-drug sensitivity, Patterns, 2021, 2: 100360.

[10] Jiang, Shengwei; Zhao, Haoran; Zhang, Weijie; Wang, Jiaqi; Liu, Yuhong; Cao, Yuanxiong; Zheng, Honghui; Hu, Zhiwei; Wang, Shubin; Zhu, Yu; Wang, Wei; Cui, Shuzhong; Lobie, Peter E.; Huang, Laiqiang*; Ma, Shaohua*; An automated organoid platform with inter-organoid homogeneity and inter-patient heterogeneity, Cell Reports Medicine, 2020, 1: 100161.