Education

   2005-2010, Ph.D. in chemical biology, Central China Normal University

   2001-2005, B.S. in applied chemistry, Central China Normal University

Professional Experience

  Oct 2012-present, Lecturer and Associate Professor, Graduate School at Shenzhen,Tsinghua University

  Oct 2016-Oct 2017, Visiting Scholar, National University of Singapore

  Jul 2010-Jul 2012, Postdoctoral Fellow, Guangdong Provincial Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University

Personal Webpage

Interaction between biomacromolecule and small molecules;

Fluorescence-based biosensors using conjugated polyelectrolytes and molecular probes targeting cancer diagnosis and drug mechanism studies;

Computational biology including bioinformatics, biomarker discovery, immunology

Current Courses

Master’s & Ph.D. Advising

Research Interests

   Interaction between biomacromolecule and small molecules;

   Fluorescence-based biosensors using conjugated polyelectrolytes and molecular probes targeting cancer diagnosis and drug mechanism studies;

   Computational biology including bioinformatics, biomarker discovery, immunology

Selected Publications

[1]Weijie Chen, Chen Zhang, Huijuan Chen, Kun Zang, Sheng Hua Liu, Yuan Xie, Ying Tan,*and Jun Yin*. Near-Infrared Thienoisoindigos with Aggregation-Induced Emission: Molecular Design, Optical Performance, and Bioimaging Application. Analytical Chemistry, 93, 3378-3385, 2021. (cover paper)

[2]Bifei Li, Jianhui Li, Wei Gan*, Ying Tan*, and Qunhui Yuan*. Unveiling the Molecular Dynamics in a Living Cell to the Subcellular Organelle Level Using Second-Harmonic Generation Spectroscopy and Microscopy. Analytical Chemistry, 2021, 93, 42, 14146–14152.

[3]Junyue Chen, Tian Jin, Jingfeng Li, Xinyan Zhang, Feng Liu, Chunyan Tan, and Ying Tan*. One-Pot Simultaneous Detection of Multiple DNA and MicroRNA by Integrating the Cationic-Conjugated Polymer and Nuclease-Assisted Cyclic Amplification. ACS Applied Bio Materials. 4, 820-828, 2021.

[4]Xiaoxie Ma, Chen Zhang, Lan Feng, Sheng Hua Liu, Ying Tan,* Jun Yin*. Construction and Bioimaging Application of Novel Indole Heptamethine Cyanines Containing Functionalized Tetrahydropyridine Ring. Journal of Materials Chemistry B, 8, 9906, 2020.

[5]Junyue Chen, Tingting Fan, Yan Chen, Lizhen Ye, Chen Zhang, Feng Liu, Ying Qin, Ying Tan*, Yuyang Jiang*. Zeptomolar-level one-pot simultaneous detection of multiple colorectal cancer microRNAs by cascade isothermal amplification. Biosensors and Bioelectronics. 169, 112631, 2020.

[6]Yingle Pan, Chen Zhang, Sheng Hua Liu, Ying Tan*, Jun Yin*, Fluorescent switch based on dithienylethene with dansulfonamide in multimedium. Dyes and Pigments, 181, 108546, 2020.

[7]Tian Jin, Jiewen Zhang, Yuanfang Zhao, Xiaoting Huang, Chunyan Tan, Shuqing Sun*, Ying Tan*. Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay. Biosensors and Bioelectronics. 150, 111936, 2020.

[8]Huan Shi, Tian Jin, Jiewen Zhang, Xiaoting Huang, Chunyan Tan, Yuyang Jiang,* Ying Tan*, A novel aptasensor strategy for protein detection based on G-quadruplex and exonuclease III-aided recycling amplification. Chinese Chemical Letters. 31, 155-158, 2020.

[9]Zhiqiang Xu, Xiaoting Huang, Ming-Xing Zhang, Weijie Chen, Sheng Hua Liu, Ying Tan,* and Jun Yin*, Tissue Imaging of Glutathione-Specific Naphthalimide−Cyanine Dye with Two-Photon and Near-Infrared Manners.Analytical Chemistry,91, 11343-11348, 2019.

[10]Zhiqiang Xu, Xiaoting Huang, Xie Han, Di Wu, Bibo Zhang, Ying Tan*, Meijiao Cao, Sheng Hua Liu, Jun Yin*, Juyoung Yoon*. A Visible Near-Infrared, Dual Channel Fluorescence-On Probe for Highly Selective Tracking of Mitochondrial Glutathione. Chem. 4, 1609-1628, 2018.

[11]Shuwen Liu, Naihan Xu, Chunyan Tan, Wei Fang, Ying Tan*, Yuyang Jiang. A sensitive colorimetric aptasensor based on trivalent peroxidasemimic DNAzyme and magnetic nanoparticles. Analytica Chimica Acta. 1018, 86-93, 2018.

[12]Wei Fang, Shuwen Liu, Chunyan Tan,* Anqi Li, Ying Tan* and Yuyang Jiang. Conjugated polyelectrolytes with a label-free aptamer for specific protein photoinactivation. Analytical Methods,10, 2205-2210, 2018. (cover page)

[13]Rui Yang, Shuwen Liu, Zhenjie Wu, Ying Tan*, Shuqing Sun*. Core-shell assay based aptasensor for sensitive and selective thrombin detection using dark-field microscopy. Talanta, 182, 348–353, 2018.

[14]Huan Shi, Bibo Zhang, Shuwen Liu, Chunyan Tan, Ying Tan,* and Yuyang Jiang. A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins. Sensors, 18, 385, 2018.

Books

2005-2010, Ph.D. in chemical biology, Central China Normal University

2001-2005, B.S. in applied chemistry, Central China Normal University

Patents

Oct 2012-present, Lecturer and Associate Professor, Graduate School at Shenzhen,Tsinghua University

Oct 2016-Oct 2017, Visiting Scholar, National University of Singapore

Jul 2010-Jul 2012, Postdoctoral Fellow, Guangdong Provincial Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University

Awards and Honors

2021 Excellent Teacher of Shenzhen；

Third prize in the 9th Tsinghua University Young Teachers Teaching Competition；

Excellent Master thesis advisor of Tsinghua University