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BIO³ Master program

Weidong Xie 谢伟东

Title: Associate Professor

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Discioline

Pharmacy


Education

9/2000-7/2005, Graduate student, Institute of Medicinal Plant, Peking Union Medical College; Major: Pharmacology, Academic Degree: Ph.D

9/1993-7/1997, Undergraduate Student, Department of Pharmaceutical Sciences, Hunan University of Traditional Chinese Medicine; Major: Pharmaceutics, Academic Degree: BS


Professional Experience

1)      12/2012-present, Associate professor of pharmacology, Graduate School at Shenzhen, Tsinghua University, China

2)      12/2014-12/2015, Visiting Scholar, Pathology and Laboratory Medicine, Perelman Medical School, University of Pennsylvania, PA, USA

3)      6/2013-8/2013, Short-term visiting scholar, Bioengineering, Lehigh University, PA, USA

4)      7/2007-11/2012, Lecturer of pharmacology, Graduate School at Shenzhen, Tsinghua University

5)      7/2005-6/2007, Postdoctoral fellow of biology, Graduate School at Shenzhen, Tsinghua University

6)      9/1997-7/2000, Assistant tutor of pharmacology, Yiyang Health School, Yiyang, Hunan


Research Interests

Pharmacological research in the fields of diabetes, hyperlipidemia, and obesity.


Selected Publications

1)        Xu C, Wang W, Zhong J, Lei F, Xu N, Zhang Y, Xie W*. Canagliflozin exerts anti-inflammatory effects by inhibiting intracellular glucose metabolism and promoting autophagy in immune cells. Biochemical Pharmacology. 2018 Mar 15; 152:45-59

2)        Xin Jiang, Chenke Xu, Fan Lei, Liao Meijian, Wei Wang, Naihan Xu, Yaou Zhang*, Weidong Xie*. MiR-30a targets IL1a and regulates islet functions by acting as an inflammation buffer and response factor. Scientific Reports. 2017 Jul 13;7(1):5270.

3)        Liao M, Li B, Zhang S, Liu Q, Liao W, Xie W*, Zhang Y*. Relationship between LINC00341 expression and cancer prognosis. Oncotarget. 2017;8(9):15283-15293.

4)        Wan G#, Xie W#, Liu Z, Xu W, Lao Y, Huang N, Cui K, Liao M, He J, Jiang Y, Yang BB, Xu H, Xu N*, Zhang Y*. Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway. Autophagy. 2014;10(1):70-9.

5)        Weidong Xie, Lijun Du*. Diabetes is an inflammatory disease: evidences from traditional Chinese Medicines. Diabetes, Obesity and Metabolism. 2011; 13:289-301.

6)        Cui K, Lyu Q, Xu N, Liu Q, Zhang J, Xing W, Bai L, Liao M, He J, Yuan B, Chen D, Xie W*, Zhang Y*. Characterization of the microRNA pool and the factors affecting its regulatory potential. Integrative Biology (Camb). 2014; 6(12):1141-52.

7)        Li M, Gu D, Xu N, Lei F, Du L, Zhang Y, Xie W*. Gut carbohydrate metabolism instead of fat metabolism regulated by gut microbes mediates high-fat diet-induced obesity. Beneficial Microbes, 2014;5(3):335-44.